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In the pivotal SURMOUNT-1 trial, clinical trials showed average body-weight reduction of roughly 20.9% at the 15mg dose over 72 weeks in adults with obesity who did not have type 2 diabetes

Permselectivity of the glomerular capillary wall: III

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GIP receptor activation enhances glucose-dependent insulin secretion, promotes pancreatic beta-cell survival, and may contribute to improved lipid metabolism