The agency said it will start taking action against compounders, which are allowed to produce custom-made alternatives to brand-name drugs during shortages, for violations in the next 60 to 90 days
doi: 10.1056/NEJMoa2032183 22 PratleyREArodaVRLingvayILudemannJAndreassenCNavarriaAet al
Chattopadhyay K, Mondal MK, Roy B
Policymakers must work to enact legislation that promotes price transparency, encourages generic drug competition, and enables Medicare to negotiate drug prices
The Phase 2 and Phase 3 trials so far have shown a safety profile broadly consistent with other GLP-1 medications: gastrointestinal side effects are common, and a new signal called dysaesthesia (an abnormal skin sensation) appears more often at higher doses
Type-2 diabetic animal studies have revealed that butyrate has similar effects to metformin in reducing insulin resistance and other T2DM-associated conditions (60)