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Recently, SLC1A3, as a crucial effector of p53, has been shown to support cell survival and growth in the absence of glutamine 149

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These studies on the models have elucidated how this immune-mediated activation of the thyroid gland leads to systemic effects, such as the presence of goiter or the clinical symptoms of hyperthyroidism, which are weight loss, increased heart rate, and nervousness (Wmeau et al