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Whether the breadth translates to clinical benefit on intact human skin depends entirely on whether the molecule reaches the cells whose gene expression it modulates

In senescent cells, FOXO4 binds to p53, preventing apoptosis

Boosts immune and nerve cell health

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To identify BPC157-FBXO22-dependent effectors, we treated HUVECs with BPC157 for 24 h and analyzed protein expression via Western blotting

This signaling cascade contributes to appetite suppression, delayed gastric emptying, and weight reduction (172)