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Anyone considering a GLP-1 drug should talk with both their primary care or obesity medicine doctor and their neurologist, says Ali

Rosmarinic acid cannot penetrate the bloodbrain barrier via oral administration, and even after intraperitoneal or intravenous injection, only extremely low levels are detected in the brain, failing to reach effective pharmacological concentrations (Calabrese et al., 2024)

Limit processed foods such as junk foods, refined sugars, and frozen meals

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For the latter, it is not only known that PAR2 signaling induces IR in adipocytes (125), but PAR2 might also be a substantial contributor to inflammatory and metabolic dysfunction (126)