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The afferent input generated by formalin is believed to release excitatory amino acids and peptides as inflammatory signaling molecules, which, through NMDA and NK1 receptors, initiate a cascade
Despite these promising findings, it is critical to evaluate safety, as there is a significant lack of comprehensive clinical trials to establish the safety or efficacy of BPC-157 in humans
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doi: 10.1177/15563316251355551
safety, immunological response, and clinical outcome
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