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When managing patients taking opioid analgesics, particularly those who have been treated for an extended period of time, and/or with high doses for chronic pain, ensure that a multimodal approach to pain management, including mental health support (if needed), is in place prior to initiating an opioid analgesic taper

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Injecting in the same location repeatedly leads to lipodystrophy (hardened or damaged fat tissue), scar tissue buildup, and increased injection site reactions

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Cystathionine -synthase and cystathionine -lyase play crucial roles in the metabolism of cysteine, a non-essential amino acid that is important for various physiological processes in the body