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Additionally, higher-dose semaglutide formulations (such as Wegovy 2.4 mg, licensed specifically for weight management) may be appropriate for certain patients meeting specific NICE criteria (TA875), though this requires specialist weight management services and is typically limited to a 2-year treatment duration

What tirzepatide is and why reconstitution matters Before you touch a syringe, you need to understand what you are working with

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Weight Loss Results at 48 Weeks: Key Percentage Findings At 48 weeks, the 12 mg retatrutide dose produced a mean body weight reduction of approximately 24.2%, compared with approximately 2.1% in the placebo group, with weight loss still ongoing at trial end