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Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have been studied extensively in the last decade and are well suited for the management of T2D in primary and secondary care, owing to their glucose-lowering and weight-loss properties and low intrinsic risk of hypoglycaemia, as well as cardiovascular (CV) benefits [6, 7]

not approved Tirzepatide (Zepbound) Approved (Zepbound, Mounjaro) Semaglutide alone (Wegovy) Approved (Wegovy, Ozempic) Cagrilintide alone Investigational Feature Head-to-head data CagriSema Did not meet non-inferiority vs tirzepatide at 84 wks (Reuters Feb 2026) Tirzepatide (Zepbound) Semaglutide alone (Wegovy) Cagrilintide alone These compounds are not interchangeable

Imbalances can affect mood, energy, and long-term metabolic resilience

Some individuals may experience mild injection-site reactions (e.g., redness, swelling) or occasional headaches

The entire plant including the leaves, stems, and flowers is used to make chanca piedra supplements