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Note the timing of bowel changes, meal size tolerance, and nausea patterns

The potential of GLP-1RAs to induce psychiatric adverse events is biologically plausible given the widespread expression of GLP-1 receptors in the central nervous system,167 their influence on neurocognitive function,168 and their effects on inflammation, stress response, and energy metabolism, which theoretically could improve mood.169 A meta-analysis170 of 11 RCTs investigating the relationship between GLP-1RAs and mental health reported 318 and 281 psychiatric adverse events in the GLP-1RAs and control groups, respectively, with no evidence of publication bias and no significant differences between the GLP-1RAs and placebo groups

The rise of digital health platforms and direct-to-consumer services has also made it easier for people to get prescriptions online and have them fulfilled through this channel

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Finamore A, Palmery M, Bensehaila S, Peluso I