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These may include: Carpal tunnel syndrome: Long-term elevation of growth hormone levels may lead to symptoms associated with carpal tunnel syndrome, such as numbness or tingling in the hands and fingers

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Data collection and analysis were not performed blind to the conditions of the experiments but randomization was incorporated for different omic layers

One canonical way for -KG to regulate gene transcription is to act as an epigenetic cofactor for Fe 2+ -dependent and 2-oxoglutarate-dependent dioxygenases (2OGDDs), including TET DNA demethylases and Jumonji C domain-containing histone demethylases (JMJD3 and UTX) 16,42,43