Haematologica 87:550551 Acknowledgements The authors are extremely thankful to the staff of the hematology department for their assistance in gathering the patient files and sparing us the time to conduct this study
This review focuses on the expression, regulation and evolution of GPX3 in non-neoplastic diseases, assesses its potential as a prognostic and diagnostic biomarker and explores new therapeutic avenues targeting GPX3
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7,8 Therefore, the dynamic NAD + and its metabolites levels, in response to diverse cellular stress and physiological stimuli, rewire biological processes via post-synthesis modification of fundamental biomolecules, including DNA, RNA and proteins