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Obesity (Silver Spring) 19, 298304, doi: 10.1038/oby.2010.181 (2011)

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doi: 10.1053/j.tcam.2008.08.003

In a neonatal rat model of hypoxiaischemia, stimulation of the TLR4p38 MAPK signaling pathway induced the production of proinflammatory cytokines, including IL-1, IL-6, and IL-18, while simultaneously downregulating the ferroptosis-related proteins SLC7A11 and GPX4, thereby promoting neuroinflammation and ferroptotic cell death [120]