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If pregnancy occurs during treatment, phentermine should be stopped immediately, and the patient should be informed of the risks

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Effects on curvature and plaque were not evaluated in the randomized phase but curvature improvements were noted in 23% of patients and plaque reductions in 47% of patients in the open-label phase

This not only poses a risk to the individuals health but also contributes to broader public health issues, such as the opioid crisis, where benzodiazepines are frequently misused in conjunction with other substances

A trial could plausibly show sustained appetite suppression and weight loss (the appetite arm holding) alongside a fading gastric-emptying delay (the motor arm adapting)

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