The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint
More clinical evaluations are needed to firmly establish the role of DSIP in human sleep and central nervous system disorders
Certain medications, including specific antiepileptics and tuberculosis drugs, can interfere with vitamin B6 metabolism, potentially causing a deficiency
When reconstituting peptides for multi-use research protocols, Bacteriostatic Water is the undisputed gold standard
Given the variability of results and the diversity of the equine microflora, additional studies are needed before excluding any potential beneficial effects of probiotics or prebiotics in horses with gastrointestinal disease
Individuals with certain medical conditions or health concerns, such as kidney disease, liver disease, certain blood disorders, or allergies to specific vitamins, may need to avoid or modify the therapy