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A 2025 Nature Medicine study of 200,000+ patients found: 2.02.5x higher risk of drug-induced pancreatitis Higher incidence of kidney stones and arthritis Chronic pancreatitis can permanently damage the pancreas and raises long-term cancer risk

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Hui H, Farilla L, Merkel P, Perfetti R (2002) The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects

While these symptoms are nonspecific, they may indicate hypomagnesemia, especially in patients with chronic diarrhea, malabsorption, or poorly controlled diabetes

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