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These results suggest that the decline in glutathione in neurons is more critical for the brain atrophy than that in astrocytes

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Therefore, the risk to humans is uncertain and those with a personal or family history of medullary thyroid carcinoma should avoid GLP-1 receptor agonists unless otherwise advised

More recently, a 2024 report titled "Assessing the Economic Impact of Obesity on Employers" found that untreated obesity in the workforce costs $146.5 billion in additional medical expenses each year, along with significant productivity losses tied to absenteeism, presenteeism, and disability

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