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It has an acetyl group (COCH3) attached to the sulfur in cysteine of the glutathione molecule

Ferroptosis is a RCD caused by intracellular iron accumulation combined with disruption of antioxidant systems, such as GPX4 inactivation and GSH depletion, and subsequent accumulation of toxic lipid peroxides (Dixon et al., 2012

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The activation of caspase-1 triggers the cleavage of GSDMD, releasing its N-terminal fragment, which translocates to the plasma membrane and forms pores, inducing pyroptosis