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Animal carcasses were collected 72 h after administration

The introduction system to the instrument was a PerkinElmer S23 autosampler coupled to a SeaSpray glass nebulizer fitted to a quartz cyclonic spray chamber

Safety, Side Effects, And Interactions General Safety Profile Methyl B-12 nasal spray is generally well tolerated when used as directed

Lessieur, E

The lipotropic agents (methionine, inositol, choline) are pH-sensitive and oxidise rapidly once exposed to air and moisture, which is why the 72-hour window exists rather than the 28-day stability window you'd see with straight methylcobalamin

Proper technique ensures the active ingredient is fully dissolved and evenly distributed