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The excess of Th17 cells in SLE patients exacerbate immune dysregulation, causing severity and progression of the disease (117)

Today the molecule remains an important research tool in laboratory studies exploring protein-mediated signalling networks and cellular regulatory mechanisms

Morciano G, Bonora M, Campo G, Aquila G, Rizzo P, Giorgi C, et al

In addition to energy production, mitochondria perform other cellular functions: Transport and storage of calcium ions used for cellular processes like muscle contraction and signal transduction Release of certain proteins to initiate programmed cell death Regulation of cell differentiation and growth Synthesis of heme, a molecule needed for hemoglobin production hemoglobin carries the oxygen transported by red blood cells Glutathione supports mitochondrial health by neutralizing harmful reactive oxygen species (ROS) that are byproducts of energy metabolism

This is the version that gave the compound its identity