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In diabetic patients, a lack of vitamin B12 in the future can lead to or speed up the development of distal symmetrical and autonomic neuropathy (Langan and Goodbred, 2017)
This dual mechanism is why tirzepatide produces greater weight loss in clinical trials and why the dosing numbers look completely different
Key drugs like semaglutide (Ozempic/Wegovy) and the dual agonist tirzepatide (Mounjaro/Zepbound) are at the forefront of a paradigm shift in treating metabolic disease
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