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We also found that GLP-1R interacted with the PKA/CREB pathway and that liraglutide could activate PKA/CREB signals and inhibit the expression of inflammation-related proteins

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An important practical distinction between the DPP-4-resistant GLP-1 agonists and DPP-4 inhibitors is the fact that GLP-1 agonists have to be injected subcutaneously, while the DPP-4 inhibitors are all oral agents

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