After 1 year of this treatment, a cessation of further gain was observed for the first time, with BMI decreasing to 50.3 kg/m 2 - a level that remained elevated but suggested a halt in disease progression
In a double blinded randomised study, daily injections of semaglutide (0.4 mg) in obese patients resulted in an average of 14% decrease in body weight, over placebo, after a year
65,66 A network meta-analysis ranked SEMA 0.4 mg first in the resolution of MASH among alternative treatments [surface under the cumulative ranking (SUCRA) = 0.89], higher than liraglutide (SUCRA = 0.84) and resmetirom (SUCRA = 0.44)
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But, like other medications in the market, the pricing of GLP-1 agonist medicationsregardless of administration methodmay vary depending on health insurance coverage and other factors such as supply and demand. Will GLP-1 drops really take off
Understanding these can help patients make informed decisions when exploring their options, particularly in the private sector where pricing is less standardised