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Vision changes in diabetic patients
Puerarin-loaded PLGA were orally administered to Sprague-Dawley rats, where pharmacokinetic analysis showed a 10.52-fold increase in plasma bioavailability and a 6.46-fold increase in brain puerarin accumulation compared to oral administration of free puerarin
This 48-week, phase 2, dose-ranging trial enrolled 338 adults with obesity (BMI 30) but without diabetes, randomising participants to placebo or one of four retatrutide doses: 1mg, 4mg, 8mg, or 12mg administered subcutaneously once weekly
Real-Time Eligibility Verification Proper eligibility verification prevents most rejections
Another described the experience as the "worst customer service" they had ever encountered, noting that email was the only contact method and responses sometimes took several days