Attenuation of renovascular damage in zucker diabetic fatty rat by NWT-03, an egg protein hydrolysate with ACE- and DPP4-inhibitory activity
It works by replicating the bodys natural hormone GLP-1, which is responsible for regulating appetite, digestion, and blood sugar balance
Until 1992, exenatide, which shares 53% homology with GLP-1(7-37), was discovered from venom of Gila monster
For diabetes patients, A1c reductions of approximately 1.0-1.5 percentage points are common with GLP-1 receptor agonists, while tirzepatide has shown reductions of up to 2.0-2.3 percentage points in clinical trials
Policymakers should prioritize measures that allow compounded versions of GLP-1 medicines in the market while accelerating the development of generics
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