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Figure 2 4 Pathogenesis and tumor microenvironment Breast cancer is an ecosystem that contains both malignant cells and stromal cells and are characterized by a substantial change in the surrounding stroma, or TME, essential for cancer growth and progression

While the lack of significant differences in heart rate overall may suggest that L-carnitine does not directly affect the cardiovascular response, the early-stage reduction in heart rate supports the idea that supplementation could improve the body's ability to handle increasing workloads more efficiently (Table 3)

Adverse health effects have been observed at both extremes of intake, with a narrow optimum range

Smalley-Freed, W

It arrives as a lyophilized powder and needs to be reconstituted before use

J Environ Manage