Lin, Andrew Emili, Stephen R
You're more likely to get melanoma if you have: Symptoms If your melanoma has spread to other areas, you may have: Hardened lumps under your skin Swollen or painful lymph nodes Trouble breathing, or a cough that doesn't go away Swelling of your liver (under your lower right ribs) or loss of appetite Bone pain or, less often, broken bones Headaches, seizures, or weakness or numbness in your arms or legs Weight loss Fatigue Getting a Diagnosis Before you have any tests, your doctor will want to know: If you havent already been diagnosed with melanoma, your doctor will do a skin exam
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Yamaguchi Y, Itami S, Watabe H, Yasumoto K, Abdel-Malek ZA, Kubo T, Rouzaud F, Tanemura A, Yoshikawa K, Hearing VJ: Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation
Gastrointestinal mucosal integrity (preclinical models)
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