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Start with 250mg, gradually increase up to 1000mg as needed, ideally under medical supervision
This systemic condition arises predominantly due to the interplay of two key components: (a) compromised insulin production by the pancreatic -cells, and (b) the failure of insulin-sensitive tissues to react to insulin
Continuous exposure to any signaling molecule can lead to receptor downregulation, meaning the body responds less strongly over time
While 2.5 mg is commonly used as the starting dose, many patients remain on it longer under medical supervision because it continues producing healthy, sustainable results
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