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10.1016/S0969-2126(98)00074-4 104 RouhierN.CouturierJ.JacquotJ

Pharmacogenetics of the G protein-coupled receptors

However, activation of caspase-3 was not essential for the execution of apoptosis-like cell death of RBCs, resulting in the hypothesis that caspases were required for appropriate erythropoiesis [23]

This suggests that, compared to the requirement for GSH synthesis in embryonic development 14,15,16 , GSH synthesis is dispensable to several organs in adult animals

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