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doi: 10.1016/j.jhep.2015.08.018

Those with psoriasis have a markedly increased risk of developing other major inflammatory disorders, particularly: cardiovascular disease diabetes metabolic syndrome stroke Note: This link between psoriasis and systemic health is underscored by a 5-year diminished life expectancy among those with the disease, largely attributable to increased cardiovascular disease risk

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The historical significance of methylene blue extends beyond its initial synthesis, as its applications have evolved and expanded over the years

doi:10.1016/j.redox.2019.101223

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