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Whole-Blood Glutathione Increased in both groups: Transdermal: 9% (977 275 to 1,075 336 mol/L) Oral: 12% (984 371 to 1,106 317 mol/L) Neither change reached statistical significance (NS)

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The agents also appear to be anti-inflammatory by suppressing the production of inflammatory mediators originating from monocytes (Table 2 describes RCTs that investigated the efficacy of peppermint oil in approximately 500 IBS patients