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ISF (30 ml/kg, po), compared to control solution, significantly increased pERK1/2 expression in both NG neurons and medial NTS at 30 min after injection ( Figures 2B, C, F, G, J, K, N, O )

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The review included a comprehensive search of peer-reviewed articles published between January 2010 and November 2024 conducted using the PubMed and Medline databases, supplemented by the inclusion of relevant studies from earlier periods when clinically justified