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While glutathione skin-lightening creams and injections are available, these uses are more common in Asia, and there are safety concerns with high-dose glutathione for cosmetic purposes

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Specifically, WG-treated HSC-T6 cells showed mitochondrial ridge breakdown and condensation, and WG alleviates liver fibrosis via enhancing ferroptosis in HSCs by regulating SLC7A11, GPX4, and GSH (Liu et al., 2022)