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The perfusion of 5-fluorouracil (5-FU), a common chemotherapeutic agent, through the vascular channel of the device, consistently exhibited expected hematotoxicity at clinically relevant low micromolar concentrations across six donors of CD34 + progenitor cells, demonstrating the reliability and relevance for toxicity testing

In a cohort study of 38 children with congenital cataracts, a missense mutation in CYP51A1 was identified in one family [79]

Iranian Journal of Pharmaceutical Research 18(3):14191428 Ahuja M, Ammal Kaidery N, Yang L, Calingasan N, Smirnova N, Gaisin A et al (2016) Distinct Nrf2 signaling mechanisms of fumaric acid esters and their role in neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced experimental Parkinsons-like disease

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Guaifenesin: (Moderate) Use caution when using dexpanthenol with drugs that decrease gastrointestinal motility, such as opiate agonists, as it may decrease the effectiveness of dexpanthenol