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If significant GI symptoms occur, slower titration, temporary dose reduction, or interruption may be necessary, with monitoring of renal function

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doi: 10.2147/IJGM.S343046 73 TranANWalkerKHarrisonDGChenWMobleyJHocevarLet al

For balance between cohorts (semaglutide users and non-users), 1:2 nearest-neighbor propensity score matching was applied to account for demographic factors, contraindications for semaglutide, indications for semaglutide use, and use of NAION-associated drugs

The best choice for you will depend on your health history, goals, and personal preferences