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A review of 19 RCTs (Randomized Controlled Trials) also demonstrated that, compared to placebo, persons with primary insomnia who used melatonin supplements slept longer (an 8-minute increase in total sleep duration) and had a 7-minute shorter sleep latency (the time it took to fall asleep)

A call for interdisciplinary research and collaboration is therefore paramount

Future research should focus on elucidating their mechanisms of action, optimizing extraction and synthesis methods, and conducting comprehensive toxicological assessments to facilitate their safe and effective utilization in healthcare and industry

doi: 10.1111/nyas.14962 42 SinhaSKatariaAKollaBPThusiusNLoukianovaLL

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