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Inside these cells, vitamin B12 is once again released and transported by another protein called Transcobalamin II to the lymph, liver, and tissues [101,102,103]

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Systemic side effects are rare at low doses, with transient nausea or mild headache reported infrequently

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These findings are generally similar to the presentation of Xu and colleagues [258] and He and colleagues [259]

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Genetic variants including GIPR rs1800437 , GLP1R rs6923761, FTO rs9939609, and MC4R rs17782313 relate to the biological pathways these medications act on

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