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This effect is likely due to the drugs ability to reduce brain inflammation, improve insulin resistance, and lower the impact of Alzheimers biomarkers

66 Other changes can reflect consequences of the intestinal disease, such as azotemia or hemoconcentration reflecting dehydration, 58 or hypokalemia reflecting inappetance

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In both cases, experimental ED30 values were lower than the theoretical values, resulting in an interaction index lower than 1 ( Table 2 )