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3: GLP-1

For complete dosing instructions, consult the official Trulicity prescribing information

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Trends Endocrinol Metab TEM

Unlike normal cells, which utilize glutamine for basal nitrogen/energy homeostasis, PCa cells elevate glutamine uptake and catabolism to meet biosynthetic demands (28, 29).Glutamine-derived carbon undergoes reductive carboxylation to generate acetyl-CoA for fatty acid synthesis, while its nitrogen is channeled into nucleotide biosynthesis (30)