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Anaphylactic reactions to thiamine are exceedingly uncommon (estimated incidence well below 1 %), but they have been documented

Smith, Sleep problems as possible predictors of intensified symptoms of autism

In diet-induced obese (DIO) mouse models, 5-Amino-1MQ treatment produced significant reductions in body weight, white adipose tissue mass, and adipocyte cell size without significant effects on food intake suggesting a metabolic rather than appetite-suppressing mechanism

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Most protocols divide administration into loading and maintenance phases

2008;2:CD002788