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AGEs can stimulate ROS production as a result of binding to RAGE (receptor for AGEs) [105]

Dono A, Torres J, Nunez L, Arevalo O, Rodriguez-Quinteros JC, Riascos RF, et al

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However, FSP1 must be myristoylated and recruited to lipid membranes to execute its reductase function [83]

BPC-157 demonstrates effectiveness for tendon and ligament healing in preclinical animal models, though confirmed human efficacy data does not exist in published clinical trials