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At the starting dose of 2 mg per week, one vial lasts five weeks
B.DeisserothK.JanakP
Int J Dermatol 58(10):12021204
However, these findings cannot be extrapolated to transdermal delivery without specific evidence demonstrating equivalent bioavailability and pharmacokinetics
At 90 kg that's 0.9 to 1.8 kg of ordinary noise
The STEP-1 body-composition substudy (n=140 DXA cohort) of semaglutide (Wegovy at 2.4 mg weekly) reported fat-free mass loss of approximately 6.9 kg over 68 weeks, accounting for approximately 45% of total weight loss based on the body-composition substudys own arithmetic and the Conte 2024 systematic review [6, 7]
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