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doi: 10.1530/ERC-19-0163 95 FallahiPFerrariSMPiaggiSLuconiMCantiniGGelminiSet al

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5, whereas hereafter we describe the significant changes across the ten most abundant genera

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The scope of the review is intentionally selective rather than exhaustive, focusing on peptidereceptor systems that demonstrate biological plausibility, mechanistic coherence, and unmet therapeutic potential, yet lack approved therapeutic analogs or advanced clinical programs