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Doses of 5001,500 mcg/day are safe and effective

Depending on your levels of deficiency or energy needs, B12 injections are commonly given weekly or monthly

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For observational studies reporting serum vitamin B12 levels, the certainty of evidence was upgraded from low to moderate due to the large and consistent magnitude of effect across studies, despite heterogeneity

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Annals of the American Thoracic Society, 13 (Suppl 5), S422-S428