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Methylcobalamin cannot be made by plants or by animals

There are studies showing that if you dont have any diagnosable diseases so youre not insulin resistant, you dont have cardiovascular disease, you dont have cancer, youre not obese but you have a low cardiorespiratory fitness, it is as bad or worse in terms of your all-cause mortality, your predicting mortality, than having cardiovascular disease or smoking or having hypertension or these things that we know are really bad for health

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That concentration matches the salt level of human blood and cellular fluid, which is what makes saline isotonic