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Summary of different animal models are listed in Table 2

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Antioxidants protective effect on the cardiovascular system is often achieved by regulating metabolism

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NTR1 agonists can exert neuroprotective effects and improve cognitive function by alleviating excessive microglial activation and inhibiting oxidative stress, cell apoptosis, and synaptic loss in the hippocampus [67, 68]

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Refrain from massaging the injection site to prevent irritation

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Sec-Gpxs are able to use Trx, and C-Gpxs GSH, but the rate of reaction is significantly decreased for the non-preferred substrate

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Depriving human cells of ergothioneine leads to accelerated DNA damage and cell death

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