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Pregnane X receptor regulates liver size and liver cell fate by Yes-associated protein activation in mice
Cell Reports (2018) 10.1016/j.celrep.2018.05.054 Follow-up study showing that p53 mutations (common in cancer cells) confer resistance to FOXO4-DRI, highlighting the p53-dependent mechanism and the importance of functional p53 for the senolytic effect
Zaletel K, Gaberscek S
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After consulting a doctor, he tried BPC-157
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