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Management typically involves lifestyle modifications, including dietary changes and regular physical activity, alongside pharmacological interventions such as metformin, SGLT2 inhibitors, or GLP-1 receptor agonists as recommended by NICE guideline NG28

Gut Microbiota Health : Lemon compounds, particularly pectin and flavonoids, may support the growth of beneficial gut bacteria

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PlexusDx requires baseline metabolic screening before starting therapy to identify contraindications and ensure safe, effective treatment

This raises questions about whether there are mechanisms regulating co-secretion, and if that regulation can be manipulated for therapeutic value