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doi: 10.2337/db05-1145 Summary Keywords GLP-1RA, tumor diseases, function, mechanism, agonists Citation Ji L, He X, Min X, Yang H, Wu W, Xu H, Chen J and Mei A (2024) Glucagon-like peptide-1 receptor agonists in neoplastic diseases

Regrowth follows correction of deficits, often over months, with earlier improvement once nutrition is rebalanced

Cardiovascular disease is the leading cause of death in both men and women in the US and globally

The hypothesis is that by avoiding -arrestin recruitment, a GLP-1 agonist like CT-996 could lead to less receptor desensitization, decreased internalization, and improved long-term efficacy and tolerability

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PMC 3875920