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In vascular endothelium and myocardium, GLP-1R activation up-regulates eNOS via PI3KAkt, increases nitric-oxide bioavailability, and reduces NF-B-mediated inflammation, translating into improved endothelial function, lower blood pressure, and attenuation of post-infarction remodeling [14]

Isolated human HFs were cultured in a 35-mm culture dish containing 1.5 ml complete hair follicle culture medium

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